Jean de Dinteville, French Ambassador to the court of Henry VIII of England, and Georges de Selve, Bishop of Lavaur. The painting is famous for containing, in the foreground, at the bottom, a spectacular anamorphic, which, from an oblique point of view, is revealed to be a human skull. Armenian carpet vishapagorg rug from the Central Anatolia is on the table.
Original public domain image from Wikimedia Commons